Hexylresorcinol Supplier - Beri Pharma - Hexyl Resorcinol (Cas 136-77-6)
BeriCos® HR Hexyl Resorcinol
Product name: Hexylresorcinol(HR)
chemical Name: 4-Hexyl-1,3-benzenediolINCI: Hexylresorcinol
Molecular weight: 194.27
Molecular formula: C12H18O2
CAS No.: 136-77-6

Application guidance
Security Data & Laws and Regulations
• Europe: Permitted in personal care products
• USA:Permitted in personal care products
• Japan:Permitted in personal care products
• China:Permitted in personal care products
Acute toxicity:
• Rat Oral LD50:550mg/kg;
• Mice transoral LD50:1040mg/kg;
• Mouse abdominal cavity LD50:335mg/kg;
•
Mouse subcutaneous LDLo:750mg/kg;
•
Mouse pathway unknown LDLo:100mg/kg;
• Guinea pig transoral LDLo:440mg/kg;
Additional multi-dose data:
• Oral TDLo of rats: 16250mg/kg/13W-I;
• Mice transoral TDLo: 32500mg/kg/13W-I;
• Tumorigenic data: Mice transoral TDLo: 64mg/kg/2Y-C;
• Reproductive data: Subcutaneous exposure to
TDLo 1 day before mating: 5mg/kg;
• Mutagenicity data: Bacteria-E. coli DNA repair system: 3mg/disc;
• Mouse lymphocytes: 5ug/L;
• Skin/eye irritation data: Rabbit eye contact: 2mg.
Efficacy
Whitening effect
The inhibitory effect of hexylresorcinol on human tyrosinase was better than that of phenylethylresorcinol, kojic acid, arbutin and hydroquinone.
The whitening effect of 4-hexylresorcinol is stronger than 377, 5 times stronger than kojic acid, and 65 times stronger than arbutin.
Anti-aging effect - Improves wrinkles and skin condition
Study (below) used HR or a combination of HR+ niacinamide to increase collagen content, effectively promote collagen synthesis and improve skin condition.
Anti-inflammation and anti-acne
HR itself has good antibacterial and bacteriostatic ability (table below)
• Studies have shown that after 6 weeks of use with a 3% active compound (HR with ethyl linoleate), acne conditions are significantly improved, while the overall skin tone is brightened.
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